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KMID : 0377619650080030307
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Korean Jungang Medical Journal
1965 Volume.8 No. 3 p.307 ~ p.311
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Absorptjen of Redioactive Iodine(1^(131)) in The Urinary Bladder of The Rabbit
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Abstract
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A study was made on absorption of Radioactive iodine (I^(131)) in the urinary bladder of the rabbit. Activity of blood sample drawn at certain intervals from 15 minutes up to 6 hours following introduction of NaI^(131) into the bladder was measured with well counter.
1) Following administration of 2 ml. of solution containing 20μC of I^(131), average count . per minute of 1 ml of blood sample was 343 at 15 minutes, 688 at one hour, 1116 at 3 hours and 1449 at 6 hours, respetively.
There was steady increase in CPM with passage of time, indicating the defnite evidence of absorption of I^(131) in the urinary bladder.
2) Effect of different solution on the absorption of I131 was studied using both distilled water and saline solution with different concentration. With distilled water, activity was always higher than one with either physiolocal or 3% saline solution, irrespective of intervals at which it was measured. Activity with distilled water is 2 times and 3 times that with either physiological or 3% saline solution at 3 and 6 hours, respectively.
3) No significant difference in activity between 3% saline and physiological saline solution was found.
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